Enzymes are widely used in dermatology and cosmetics. The enzymes improve skin appearance and prevent skin problems and enhance the beauty of the skin. Coenzymes and Cofactors in these enzymes promote healthy skin. Enzymes used for cosmetics are majorly sourced from plants. They are called proteolytic enzymes and their role is to break down the proteins. They break down the keratin protein in the upper layer of the skin, which bonds dead skin cells together. This results in smoother, softer skin and also helps diminish acne, scars and pigmentation.